Cancer Research
We have EAC (Ehrlich ascites carcinoma) cell facility which is used for cancer research. Isolation of bioactive compound, investigation of their effect on cancer cell line in mice model and molecular detection of the differential expression pattern of cancer-related genes (BAX, BCL2, P53, Caspase 3, Caspase 8, Caspase 9, TNFa, NFkB PARP, PTEN) in cancer cells in response of these compounds).
Snake Venom Research
Biochemical characterization of venom from venomous snakes of Bangladesh and evaluating the efficacy of the antivenom used against snake bite treatment; Identification and characterization of novel physiologically interesting protein/peptide as drug lead compound
Medical Genetics Research
Medical genetics involves the studies of inheritance, mapping mutated gene that may cause diseases, diagnosis, treatments etc. Here in our lab MBPSL, We focus our research to find out disease causing gene/s or mutation/s, try to find out easy to use diagnosis procedure, best practices of treatment and management.
Plasma Agriculture Research
Plasma is one of the four fundamental states of matter which contains a significant portion of charged particles. These particles are of great importance in the field of agriculture for their low-cost and environmentally friendly applications. Thus, MBPSL has worked on several different types of plasmas (DBD, LPDBD, LFGD, Air etc.) as well as plasma-activated water (PAW) which have increased germination rate, plant growth, nutritional contents etc. significantly.
Microbiology Research
From Bacteria to Fungus, MBPSL focuses on isolation, characterization and identification of key microbes that have impact on human life. A major area of research here is also the production of recombinant protein through recombinant DNA technology.
List of Publications
Impact of LFGD (Ar+O2) plasma on seed surface, germination, plant growth, productivity and nutritional composition of maize (Zea mays L.)
In this present study conducted with the LFGD (Low-Frequency Glow Discharge) (Ar + O2) plasma treated maize seeds, to inspect the effect on seed surface modifications, seed germination, growth, development, productivity and nutritional compositions of maize plants. This study reported that LFGD (Ar + O2) plasma treated maize seeds have a potential effect to change its smooth seed surfaces and, it becomes rougher. It also enhances the seed germination rate up to...
LFGD (Ar + O2) plasma treatment showed a potential impact on the maize cultivation system, which is very effective tools and both in nationally and internationally alter the conventional cultivation system of maize. Because it promotes seed surface modification, improved germination rate, shoot length, root length, chlorophyll content, some of the growths related enzymatic activity, nutrient composition, iron, and zinc micro-nutrients and the productivity of maize... Read more...
Heliyon 2021 vol 7 : Issue 3
Research article | Published on March, 2021
Improvement of Seed Germination Rate, Agronomic Traits, Enzymatic Activity and Nutritional Composition of Bread Wheat (Triticum aestivum) Using Low-Frequency Glow Discharge Plasma
Plasma agriculture is an emerging field. In this report, we studied the effect of medium pressure (~ 10 torr) low-frequency (3–5 kHz) glow discharge (LFGD) plasma on various agronomical and physiological attributes in wheat. Wheat seeds treated by LFGD plasma generated from Argon–Oxygen (Ar + O2) gas mixture and air showed a remarkable enhancement in seed germination by 12.38% and 7.14% respectively. Also, the morpho-physiological features significantly improved due to plasma treatment relative to control. In germinated wheat seedlings, H2O2 concentration markedly increased due to plasma treatments, suggesting that LFGD may be involved in nitrogen signaling in wheat. Analysis of wheat plants germinated from plasma treated seeds showed a notable increase in total soluble sugar and protein subjected to Ar + O2 plasma treatment. Results also revealed a significant increase in TGM, iron, manganese, fat, and ash content while moisture content significantly decreased in wheat grain due to plasma treatments relative to controls. Read more…
Plasma Chemistry and Plasma Processing 2021
Research article | Published on 07 March 2021
A comparative study of biological potentiality and EAC cell growth inhibition activity of Phyllanthus acidus (L.) fruit pulp and seed in Bangladesh
Phyllanthus acidus (L.) is a widely distributed herbal medicinal plant naturally used in Ayurvedic medicine in Bangladesh. The present study focused on exploring the biological potential as well as the inhibitory effect of EAC cell growth with a comparative analysis between Phyllanthus acidus fruit pulp and seed. Crude methanol extract of P. acidus (MEPA) fruit pulp and seed was assessed as DPPH and NO free radical scavengers. While Brine Shrimp lethality bioassay, the standard protocol of phytochemical screening and hemagglutination assay were performed successively to determine the toxic effect on normal cells, the identification of some crucial phytochemicals, and the existence of lectin protein. Based on the findings, the present study reveals that MEPA fruit pulp can be considered as a novel biological candidate for the treatment of fatal diseases shortly. Read more…
Saudi Journal of Biological Sciences (2021) Volume 28, Issue 3, Pages 2014-2022
Reseach Article | Published on March 2021
List of Posters
First case report of Lipoid proteinosis in Bangladesh: Clinical features and molecular analysis
Lipoid proteinosis is a rare autosomal recessive disorder (LP; OMIM #247100) caused by mutations in the extracellular matrix protein 1 (ECM1) gene. The disease is characterized by cutaneous and mucosal lesions, beaded eyelid papules and hoarseness appearing in early childhood. In this study , we report the clinical features and molecular analysis of a Bangladeshi patient affected by Lipoid proteinosis. The following poster was presented at International conference on the social and life sciences-2020, held in East West University, Dhaka.
International Conference on the social and life sciences (2020)
Poster Presentation | Presented on February 27, 2020
